Mark P. Goldberg, MD

PUBLICATIONS

Hobson, J. A., Goldberg, M. P., Vivaldi, E., Riew, D. (1983). Enhancement of desynchronized sleep signs after pontine microinjection of the muscarinic agonist bethanechol. Brain Res. 275, 127-136.

Goldberg, M. P., Weiss, J., Pham, P. C., Choi, D. W. (1987). N-methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture. Journal of Pharmacology and Experimental Therapeutics, 243, 784-791.

Goldberg, M. P., Choi, D. W. (1990). Intracellular free calcium rises in cultured neurons deprived of oxygen and glucose. Stroke, 21 (Suppl. III): III, 75-77.

Koh, J., Goldberg, M. P., Hartley, D. M., and Choi, D. W. (1990). Non-NMDA receptor-mediated neurotoxicity in cortical culture. Journal of Neuroscience, 10, 693-705.

Monyer, H., Giffard, R. G., Hartley, D. M., Dugan, L. L., Goldberg, M. P., Choi, D. W.[ (1992). Oxygen or glucose deprivation-induced neuronal injury in cortical cultures is reduced by tetanus toxin. Neuron 8, 1-20.

Goldberg, M. P., Choi, D. W. (1993). Oxygen-glucose deprivation cortical culture: calcium-dependent and calcium-independent mechanisms of neuronal injury. Journal of Neuroscience, 13, 3510-3524.

Moudy, A. M., Handran, S. D., Goldberg, M. P., Ruffin, N., Karl, I., Kranz-Eble, P., DeVivo, D. C., Rothman, S. M. (1995). Abnormal calcium homeostasis and mitochondrial polarization in a human encephalomyopathy. Proceedings of the National Academy of the Sciences .U.S.A., 92, 729-733.

Dugan, L. L., Sensi, S. L., Canzoniero, L. MT., Handran, S.D., Rothman, S. M., Lin, T-S., Goldberg, M. P., Choi, D. W. (1995). Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate. Journal of Neuroscience, 15, 6377-6388.

David, J. C., Yamada, K. A., Bagwe, M. R., Goldberg, M. P. (1996). AMPA receptor activation is rapidly toxic to cortical astrocytes when desensitization is blocked. Journal of Neuroscience, 16, 200-209.

Park, J. S., Bateman, M. C., Goldberg, M. P. (1996). Rapid alterations in dendrite morphology during sublethal hypoxia or glutamate receptor activation. Neurobiology of Disease, 3, 215-227.

Faddis, B. T., Hasbani, M. J., Goldberg, M. P. (1997). Calpain activation contributes to dendritic remodeling after brief excitotoxic injury in vitro. Journal of Neuroscience, 17, 951-959.

Hyrc, K., Handran, S. D., Rothman, S. M., Goldberg, M. P. (1997). Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators. Journal of Neuroscience, 17, 6669-6677.

McDonald, J. W., Althomsons, S. P., Hyrc, K. L., Choi, D. W., Goldberg, M. P. (1998). Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity. Nature Med, 4, 291-297.

Hasbani, M. J., Hyrc, K. L., Faddis, B. T., Romano, C., Goldberg, M. P. (1998). Distinct roles for sodium, chloride, and calcium in excitotoxic dendrite injury. Experimental Neurology, 154, 241-58.

Hyrc, K. L., Bownik, J., Goldberg, M. P. (2000). Ionic selectivity of low-affinity ratiometric calcium indicators: mag-fura-2, fura-2ff and BTC. Cell Calcium, 27, 75-86.

Xu, J., Chen, S., Ahmed, H., Chen, H., Ku, G., Goldberg, M. P., Hsu, C. Y. (2001). Amyloid-? peptides are cytotoxic to oligodendrocytes. Journal of Neuroscience, 21, RC118 (1-5).

Hasbani, M. J., Schlief, M. L., Fisher, D. A., Goldberg, M. P. (2001). Dendritic spines lost during glutamate receptor activation re-emerge at original sites of synaptic contact. Journal of Neuroscience, 21(7), 2393-2403.

Tekkok, S. B., Goldberg, M. P. (2001). AMPA/kainate receptor activation mediates hypoxic oligodendrocyte death and axonal injury in cerebral white matter. Journal of Neuroscience, 21, 4237-48.

Hasbani, M. J., Viquez, N. M., Goldberg, M. P. (2001). NMDA receptors mediate hypoxic spine loss in cultured neurons. Neuroreport, 12, 2731-5.

Goldberg, M. P., Ransom, B. R. (2003). New light on white matter. Stroke 34,330-2.

De Erausquin, G. A., Hyrc, K., Dorsey, D. A., Mamah, D., Dokucu, M., Masco, D. H., Walton, T., Krikor, D., Soriano, M., Verdugo, J. E., Goldberg, M. P., Dugan, L. L. (2003). Nuclear translocation of NF-KB by AMPA receptors leads to transcription of p53 and cell death in dopaminergic neurons. Molecular Pharmacology, 63(4), 784-90.

Dewar, D., Goldberg, M. P. (2003). Oligodendrocytes and ischaemic brain injury. Journal of Cerebral Blood Flow and Metabolism, 23(3), 263-74.

Istas, A. D., Labit, J. L., Bauman, A. M., Goldberg, M. P. (2003). The Stroke Trials Directory: an online registry of clinical trials in cerebrovascular disease. Seminar on Cerebrovascular Diseases and Stroke, 3(1), 48-53.

Brendza, R. P., Simmons, K., Bales, K. R., Paul, S. M., Goldberg, M. P., Holtzman, D. M. (2003). Use of YFP to study amyloid-ß associated neurite alterations in live brain slices. Neurobiology of Aging 24(8), 1071-7.

Ness, J. K., Valentino, M., McIver, S. R., Goldberg, M. P. (2005). Identification of oligodendrocytes in experimental disease models. Glia, 50(4), 321-8.

CONTACT INFORMATION

Email:
Phone: (314) 362-3259 (lab)
Fax: (314) 362-9462

Mailing address:
Department of Neurology
660 S. Euclid Avenue
Campus Box 8111
St. Louis, MO 63110